Institut für Kognitive Neurowissenschaften / Biopsychologie

Ruhr-Universität Bochum

In recent studies by our group we accumulated evidence that the effect of certain genetic polymorphisms varies across cognitive processes. The results call in question, if a ?risk allele? necessarily confers a disadvantage to its carriers. In this study we provide further evidence on this issue.
Cognitive control processes may depend on contextual information, sometimes improving performance, but impairing performance if expectancies about forthcoming events induce pre-potent responses. The neurobiological bases of these effects are not understood. Here, we examine context-dependent variations of response control processes using the AX-CPT task with respect to the relevance of the functional serotonin 1A receptor polymorphism (5-HT1A C(\xe2\x88\x921019)G). The results show that, when context information is helpful to drive behavioural performance, carriers of the \xe2\x88\x921019G allele reveal compromised cognitive control.

Type of institution:

Work focus:
Molekulare Neurobiologie, Zelluläre Neurobiologie

Universitätsstr. 150
D-44780 Bochum

0049 234 322 8213


Contact person:

Gabi Salzmann

Position / Activity: