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- Diseases
- Alzheimer's disease
Alzheimer's – a Disease makes History
After more than 100 years, Alzheimer's disease is still incurable. Possible causes are emerging.
20.10.2025
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- News from the Institutes
New diagnostic markers for multiple sclerosis discovered in brain and spinal fluid
Researchers at the MPI of Biochemistry and TUM have examined the cerebrospinal fluid of 5,000 patients with neurological diseases and discovered new diagnostic and prognostic markers for multiple sclerosis.
26.02.2026
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- Diseases
- Multiple sclerosis
Multiple Sclerosis – a Medical Challenge
Multiple sclerosis is incurable, but there are a variety of treatment options available.
20.02.2026
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- News from the Institutes
Structure of clusterin: a key protein against neurodegenerative diseases
Crystallographic three-dimensional structure of human clusterin determined for the first time
08.09.2025
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- News from the Institutes
Heat makes you sick, and the brain is particularly affected
Heat waves have been linked to an increased risk of neurological events such as strokes. But that’s not all.
04.06.2026
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- Basics
- The Glymphatic System
When the Brain gets clogged with Waste
Not even a coffee cup full of “nerve water” can flush out the brain at night – but woe betide you if you don't.
06.11.2024
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- Glossary
Parkinson's disease
Parkinson's disease is one of the most common neurological disorders, caused by the death of dopamine-producing neurons in the substantia nigra, leading to a neurotransmitter imbalance in the basal ganglia. Symptoms usually begin late in life with mild tremors (resting tremor), increasing stiffness of the limbs, and slowed voluntary movements (bradykinesia). Later, postural instability, balance disorders, and difficulty walking occur. Other typical features include rigid facial expressions (hypomimia), a shuffling gait, and muscle stiffness (rigor). The disease is incurable, but its symptoms can be treated with medication (e.g., L-dopa, dopamine agonists) or surgery involving deep brain stimulation (brain pacemaker).
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- News from the Institutes
Insight into schizophrenia disease mechanisms found in the eye
Impaired neuronal connectivity in the retina
17.02.2025
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- News from the Institutes
A switchboard with precision
How the brain licenses movements
28.05.2025
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- Glossary
Neurodegeneration
Collective term for diseases in which nerve cells gradually lose their structure or function until they eventually die. In many cases, misfolded proteins are the trigger – such as certain forms of the proteins beta-amyloid and tau in the case of Alzheimer's disease. In other diseases, such as Parkinson's disease or Huntington's disease, proteins within the neurons are not broken down properly. As a result, toxic aggregates are deposited there, leading to the respective disease symptoms. While Huntington's disease is clearly genetic, in Parkinson's and Alzheimer's there appear to be certain gene variants that promote their development. None of these neurodegenerative diseases can be cured at present.
