Search
-
- Glossary
CREB
A transcription factor in the cell nucleus that is activated by cAMP-dependent signaling pathways. CREB influences gene activity and can thus improve communication between two cells. This is a cellular basis for learning processes.
-
- Glossary
Neurodegeneration
Collective term for diseases in which nerve cells gradually lose their structure or function until they eventually die. In many cases, misfolded proteins are the trigger – such as certain forms of the proteins beta-amyloid and tau in the case of Alzheimer's disease. In other diseases, such as Parkinson's disease or Huntington's disease, proteins within the neurons are not broken down properly. As a result, toxic aggregates are deposited there, leading to the respective disease symptoms. While Huntington's disease is clearly genetic, in Parkinson's and Alzheimer's there appear to be certain gene variants that promote their development. None of these neurodegenerative diseases can be cured at present.
-
- Page
Home
24.02.2017
-
- Diseases
- Multiple sclerosis
Multiple Sclerosis – a Medical Challenge
Multiple sclerosis is incurable, but there are a variety of treatment options available.
20.02.2026
-
- News from the Institutes
A human model of the blood-brain barrier
Disruptions to the protective barrier contribute to the development of serious brain diseases such as stroke and Alzheimer's.
16.12.2025
-
- Diseases
- Intruders
Prions: Proteins That Drive You Crazy
On cannibalism, riddled brains, and contagious madness
02.05.2023
-
- Basics
- The Glymphatic System
Hidden Channels
It was a long scientific journey that led to the discovery of a waste removal system in the brain.
06.11.2024
-
- Diseases
- Multiple sclerosis
Living with, not despite, Multiple Sclerosis
A good life despite MS? Yes, it is possible!
15.10.2025
-
- Basics
- Anatomy
The Basal Ganglia
Whenever we perform a deliberate movement, core areas deep within the brain are involved.
23.08.2011
-
- Discover
- Milestones
Thomas Südhof: Many small Steps to the Nobel Prize
Thomas Südhof discovered important synaptic proteins. For this, he was awarded the Nobel Prize in Medicine.
03.12.2013
