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Media - Image | Graphic: The most important Milestones in Alzheimer's Research
For more than 100 years, researchers have been searching for the causes of Alzheimer's disease.
02.12.2025
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- News from the Institutes
New insights into immune cells in the context of neurodegeneration
Lab Findings Support the Concept that Reducing Neuroinflammation Could Help Fight Alzheimer’s
04.02.2025
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- Krankheiten
- Alzheimer's disease
How the plaques typical of Alzheimer's disease develop
Two cuts are necessary for the protein APP to form beta-amyloid.
23.09.2013
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Mediathek: Grafik & Foto
10.03.2017
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- Krankheiten
- Alzheimer's disease
Dementia worry: The Bogeyman of old Age
The fear of developing dementia oneself is widespread.
11.11.2025
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Glossar
15.03.2017
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- Glossary
Alzheimer's disease
Alzheimer's disease is a progressive neurodegenerative disorder characterized by cortical atrophy, nerve cell loss, synapse loss, and deposits of amyloid plaques and neurofibrillary tangles, leading to dementia and loss of function. Early symptoms include memory problems, speech disorders, executive deficits, depressive moods, and subtle personality changes. As the disease progresses, global cognitive impairment, aphasia, agnosia, apraxia, and behavioral abnormalities such as apathy, restlessness, and sleep disorders occur. The disease was first described in 1907 by Alois Alzheimer.
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- Glossary
Frontotemporal dementia
Frontotemporal dementia is a neurodegenerative disease. Unlike Alzheimer's dementia, Pick's disease usually begins before the age of 60 and initially manifests itself through changes in personality and social behavior. There are also variants that begin with speech disorders. In advanced stages, memory performance is also impaired. The physiological cause is degeneration of nerve cells in the frontal and temporal lobes of the brain. Similar to Alzheimer's disease, the aggregation of certain proteins appears to play a role in pathogenesis. However, doctors do not yet understand exactly what happens in this process and what other factors contribute to the development of Pick's disease. Today, classic Pick's disease is only a subtype of FTD in which characteristic Pick bodies can be detected in the brain.
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- News from the Institutes
A human model of the blood-brain barrier
Disruptions to the protective barrier contribute to the development of serious brain diseases such as stroke and Alzheimer's.
16.12.2025
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24.02.2017
