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- News from the Institutes
New diagnostic markers for multiple sclerosis discovered in brain and spinal fluid
Researchers at the MPI of Biochemistry and TUM have examined the cerebrospinal fluid of 5,000 patients with neurological diseases and discovered new diagnostic and prognostic markers for multiple sclerosis.
26.02.2026
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- Diseases
- Alzheimer's disease
A Slow Descent into Forgetfulness
After a long asymptomatic phase, Alzheimer's disease progresses through three stages
18.03.2026
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- Diseases
- Alzheimer's disease
Neuroinflammation and Alzheimer's disease
In Alzheimer's disease, among other things, the immune cells of the brain – the microglia – are overactive.
31.01.2014
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- Diseases
- Alzheimer's disease
Media - Image | Graphic: The most important Milestones in Alzheimer's Research
For more than 100 years, researchers have been searching for the causes of Alzheimer's disease.
02.12.2025
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- News from the Institutes
New insights into immune cells in the context of neurodegeneration
Lab Findings Support the Concept that Reducing Neuroinflammation Could Help Fight Alzheimer’s
04.02.2025
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- Diseases
- Alzheimer's disease
How the plaques typical of Alzheimer's disease develop
Two cuts are necessary for the protein APP to form beta-amyloid.
23.09.2013
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- Diseases
- Alzheimer's disease
Dementia worry: The Bogeyman of old Age
The fear of developing dementia oneself is widespread.
11.11.2025
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- News from the Institutes
Combating loss of function in small vessels of the brain
A new study identifies molecular factors that promote small vessel disease – and an active drug that can restore impaired vascular functions.
15.12.2025
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- News from the Institutes
A human model of the blood-brain barrier
Disruptions to the protective barrier contribute to the development of serious brain diseases such as stroke and Alzheimer's.
16.12.2025
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- Glossary
Alzheimer's disease
Alzheimer's disease is a progressive neurodegenerative disorder characterized by cortical atrophy, nerve cell loss, synapse loss, and deposits of amyloid plaques and neurofibrillary tangles, leading to dementia and loss of function. Early symptoms include memory problems, speech disorders, executive deficits, depressive moods, and subtle personality changes. As the disease progresses, global cognitive impairment, aphasia, agnosia, apraxia, and behavioral abnormalities such as apathy, restlessness, and sleep disorders occur. The disease was first described in 1907 by Alois Alzheimer.
