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- Diseases
- Successful aging
The Secret of Neural Reserve
From the hippocampus to the synapse: A research consortium is investigating which factors protect our thinking in old age
01.02.2026
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- Glossary
Lewy body dementia
A neurodegenerative disease that resembles Alzheimer's disease, but also Parkinson's disease in its symptoms. The Lewy bodies that give the disease its name are caused by protein deposits in the nerve cells of the cerebral cortex and brain stem, which impair the function of the corresponding neurons. In addition to cognitive impairment, Lewy body dementia often causes hallucinations or depression, as well as changes in mobility similar to those seen in Parkinson's disease.
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- Basics
- Communication of Cells
Neurotransmitters: Messenger Molecules in the Brain
“Happy hormone” & Co.: Without neurotransmitters, nerve cells would not be able to communicate.
05.08.2025
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- Page
The Topic Partners
27.02.2024
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- Basics
- The Glymphatic System
The Brain’s Cleanup Crew
The glymphatic system is the brain's cleanup crew, flushing away waste products.
06.11.2024
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- News from the Institutes
How Stress Disrupts the Brain’s Navigational System
Persons under stress may have a harder time spatially orienting themselves. Researchers in Bochum have discovered why.
13.03.2026
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- Diseases
- Alzheimer's disease
The Challenge of Caring for Dementia Patients
More and more people are suffering from dementia – a challenge for hospitals.
11.01.2012
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- Topic
Basic Research
Basic research is aimless. But eminently important.
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- Glossary
Neurofibrils
Neurofibrils are fine fibrous structures in nerve cells that consist mainly of neurofilaments (a form of intermediate filaments) and other components of the cytoskeleton. They run in bundles through the cell body and the extensions of neurons and contribute significantly to the stabilization and shaping of the nerve cell. They appear as characteristic features of neurons even in the early embryo. Alzheimer's disease causes profound changes in cytoskeletal structures: the protein tau, which normally stabilizes microtubules, becomes excessively phosphorylated, detaches from the microtubules, and aggregates to form the typical neurofibrillary tangles (fibrillary bundles). These are a central pathological feature of the disease.
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- News from the Institutes
Interaction between interneurons stabilizes gamma oscillations in a brain
PV+ cells act as the “conductors” of visually induced gamma oscillatory rhythm
26.05.2025
