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- Glossary
Secretases
Secretases are proteases that cleave proteins into smaller fragments, often membrane-bound in the case of transmembrane proteins. Cleavage produces intracellular fragments that can act as signals and extracellular fragments that are released into the environment. Some proteins, such as the amyloid precursor protein (APP), offer different cleavage sites for different secretases. Beta-amyloid, the main component of senile plaques, is formed when APP is first cleaved by β-secretase outside the membrane and then by γ-secretase inside the membrane.
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The Glymphatic System
The brain produces waste, too. And the brain has its own waste disposal system.
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Glossary
15.03.2017
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- Multiple sclerosis
Multiple Sclerosis – a Medical Challenge
Multiple sclerosis is incurable, but there are a variety of treatment options available.
20.02.2026
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Current: News from the Institutes
09.12.2019
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- Basics
- The Glymphatic System
Hidden Channels
It was a long scientific journey that led to the discovery of a waste removal system in the brain.
06.11.2024
