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- Alzheimer's disease
How the plaques typical of Alzheimer's disease develop
Two cuts are necessary for the protein APP to form beta-amyloid.
23.09.2013
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- Diseases
- Alzheimer's disease
Alzheimer's – a Disease makes History
After more than 100 years, Alzheimer's disease is still incurable. Possible causes are emerging.
20.10.2025
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- Glossary
Plaques
Senile plaques accumulate in the gray matter of the brain when a protein – known as amyloid precursor protein – is not broken down correctly. Inflammation and disorders of fat or sugar metabolism can promote plaque formation. On average, the deposits reach a diameter of 50 micrometers. The appearance of plaques is one of several anatomical changes in the brain that pathologists can use to diagnose Alzheimer's disease after death.
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- Diseases
- Alzheimer's disease
A Slow Descent into Forgetfulness
After a long asymptomatic phase, Alzheimer's disease progresses through three stages
18.03.2026
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- News
- Question to the brain
How do neurons change in dementia?
What changes do brain cells undergo in dementia from a neurobiological perspective?
19.07.2026
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- News from the Institutes
Structure of clusterin: a key protein against neurodegenerative diseases
Crystallographic three-dimensional structure of human clusterin determined for the first time
08.09.2025
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- News from the Institutes
Protective Brain Immune Cell State Discovered
Discovery points to a potential new therapeutic pathway for Alzheimer’s disease
05.11.2025
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- Page
Graphics & photos
10.03.2017
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- Diseases
- Intruders
It Takes More than Guts
Microbiome: How gut bacteria can make the brain sick
02.05.2023
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- Diseases
- Alzheimer's disease
Alzheimer's from the Inside
How do people live with Alzheimer's disease? A conversation with someone affected by the condition.
20.10.2025









