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How does the brain age?
What happens to the brain as we age?
25.05.2025
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- Glossary
Amygdala
An important core area in the temporal lobe that is associated with emotions: it evaluates the emotional content of a situation and reacts particularly to threats. In this context, it is also activated by pain stimuli and plays an important role in the emotional evaluation of sensory stimuli. Inaddition, it is involved in linking emotions with memories, emotional learning ability, and social behavior. The amygdala is part of the limbic system.
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- Glossary
Mamillary bodies
Two structures of the posterior thalamus (largest part of the diencephalon). Due to their similarity to the female breast, they are also called mammillary bodies. They are located at the front end of the fornix and are attributed to the limbic system.
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- Glossary
Hippocampus
The hippocampus is the largest part of the archicortex and an area in the temporal lobe. It is also an important part of the limbic system. Functionally, it is involved in memory processes, but also in spatial orientation and learning. It comprises the subiculum, the dentate gyrus, and the Ammon's horn with its four fields CA1-CA4. Changes in the structure of the hippocampus due to stress are associated with chronic pain. The hippocampus also plays an important role in the amplification of pain through anxiety.
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- Glossary
Emotions
Neuroscientists understand "emotions" to be complex response patterns that include experiential, physiological, and behavioral components. They arise in response to personally relevant or significant events and generate a willingness to act, through which the individual attempts to deal with the situation. Emotions typically occur with subjective experience (feeling), but differ from pure feeling in that they involve conscious or implicit engagement with the environment. Emotions arise in the limbic system, among other places, which is a phylogenetically ancient part of the brain. Psychologist Paul Ekman has defined six cross-cultural basic emotions that are reflected in characteristic facial expressions: joy, anger, fear, surprise, sadness, and disgust.
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- Glossary
Paraventricular nucleus
A nucleus of the hypothalamus whose neurons produce various hormones, including oxytocin and vasopressin, which are transported to the neurohypophysis. The PVN sends axons to the limbic system, the brain stem, and other hypothalamic nuclei.
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- Glossary
Cingulate cortex
A component of the prefrontal cortex located at the front of the brain. Like half a doughnut, the cingulate cortex wraps around the corpus callosum. Functionally, it belongs to the limbic system and is involved in emotion, memory, and motor function.
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- Glossary
Anterior cingulate cortex
Like the entire cingulate cortex, the anterior region of the limbic system regulates drive-controlled behavior. In the perception of pain, it is particularly associated with the affective pain component - including social pain as experienced through exclusion.
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16.06.2017
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- Glossary
Temporo-parietal junction
The transition between the temporal and parietal lobes – i.e., the temporal and parietal lobes – of the cerebral cortex. Here, in the posterior region of the Sylvian fissure, information from the limbic system, the thalamus, and the visual, auditory, and somatosensory cortex is integrated. Accordingly, the temporo-parietal junction forms an anatomical and functional hub of the brain that helps us develop complex abilities, including the ability to recognize biological movement or the ability to empathize with other people.
