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- Glossary
Posterior parietal cortex
The posterior parietal lobe receives inputs from numerous visual, auditory, somatosensory, and proprioceptive cortical areas. It integrates this information into an overall spatial picture that enables orientation, spatial attention, and the planning and execution of goal-directed movements.
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Postcentral gyrus
The postcentral gyrus is the fold on the surface of the cerebrum located immediately behind the central sulcus. It contains the primary somatosensory cortex, where touch, pressure, temperature, and proprioceptive stimuli are processed.
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Pre-dementia
Alzheimer's disease typically progresses through several clinical stages, preceded by an early phase with initial cognitive impairments. This phase, formerly known as pre-dementia, is now usually referred to as mild cognitive impairment (MCI) due to Alzheimer's disease. It can manifest itself through symptoms such as declining short-term memory. With modern imaging techniques, especially amyloid PET, characteristic amyloid deposits in the brain can already be detected in this early phase. Laboratory chemical analyses of blood or cerebrospinal fluid can also provide indications of changes in protein concentrations typical of Alzheimer's disease. Although the clinical diagnosis of dementia is only made in later stages, the underlying Alzheimer's pathology can often be detected in advance today.
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- Glossary
Prefrontal cortex
The prefrontal cortex (PFC) forms the front part of the frontal lobe and is one of the brain's most important integration and control centers. It receives highly processed information from many other areas of the cortex and is responsible for planning, controlling, and flexibly adapting one's own behavior. Its central tasks include executive functions, working memory, emotion regulation, and decision-making. In addition, the PFC plays an important role in the cognitive evaluation and modulation of pain.
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- Glossary
Premotor cortex
Part of the motor cortex in the frontal lobe. It is connected to the primary motor cortex and numerous other brain regions and is involved in the planning, preparation, and coordination of complex, voluntary movements. Examples of its functions include reaching for an object or the sequence of movements involved in targeted actions.
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- Glossary
Primary auditory cortex
The first processing station in the cerebral cortex for auditory information. The primary auditory cortex is located in the Heschl's gyrus and receives inputs from the medial geniculate nucleus of the thalamus. It is organized tonotopically – its neurons are arranged continuously according to frequency.
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Primary gustatory cortex
Term for the areas of the insular cortex where information from the taste receptors is processed. Further processing takes place in the secondary gustatory cortex in the orbitofrontal cortex.
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- Glossary
Primary motor cortex
An area of the frontal lobe in the anterior wall of the central sulcus. It is considered to be the higher-level control unit responsible for voluntary and fine motor skills. This is where the cell bodies of the central motor neurons are located, whose axons primarily extend to the spinal cord (via the corticospinal tract). Only in the primary motor cortex do Betz giant cells occur, which are particularly large motor neurons whose axons extend directly to the motor neurons in the anterior horn of the spinal cord without prior synaptic switching.
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- Glossary
Primary somatosensory cortex
Area of the cerebrum where haptic stimuli are processed centrally. Anatomically, the somatosensory cortex is located on the first cerebral gyri behind the central sulcus. This is where afferents from sensory cells throughout the body converge. Neurons that evaluate information from neighboring areas of the body are also located next to each other in the somatosensory cortex. Neuroscientists refer to this as somatotopy.S1 is an important station in pain processing – this is where we become aware of the pain stimulus.
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- Glossary
Primary visual cortex
The part of the occipital lobe whose primary inputs originate from the visual system. According to Brodmann, who originally divided the cerebral cortex into 52 areas in 1909, the primary visual cortex is area 17.
