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- Glossary
Antagonist
Due to the lock-and-key principle, transmitters (messenger substances) can only bind to specific receptors. An antagonist can be so similar to this transmitter that it can bind to this receptor. It thus prevents the actual transmitter from activating the receptor and becoming effective. There are also antagonists that do not bind directly to the receptor but alter the "lock," i.e., the receptor, so that the key no longer fits.
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- Glossary
Anterior cingulate cortex
The anterior cingulate cortex (cingulate gyrus) plays a role not only in autonomic functions such as blood pressure and heart rate regulation, but also in rational processes such as decision-making. This area of the brain is also involved in emotional processes, such as impulse control. Anatomically, the anterior cingulate cortex (ACC) is characterized by a large number of spindle neurons (Von Economo neurons). These special nerve cells have a long, spindle-shaped structure and have so far only been found in mammals such as primates, elephants, and some whale and dolphin species. Spindle neurons contribute to higher social and emotional processes such as self-awareness, empathy, and quick emotional decisions. In pain perception, it is particularly associated with the affective component of pain – including social pain, such as that experienced through exclusion.
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- Glossary
Anterograde amnesia
A form of memory disorder in which the formation of new memories – i.e., the storage of new information – is no longer possible from the time of the damage. Memories from before that time can still be recalled. Those affected usually also forget their forgetfulness.
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- Glossary
Apraxia
Difficulty performing a purposeful movement, such as grasping a glass or cutting with scissors. Depending on the form of apraxia, speech or facial expressions may also be affected. The cause is not muscle weakness or paralysis, but damage to one or more areas of the brain, e.g., as a result of a stroke. In other cases, however, it is congenital.
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- Glossary
working memory
A form of memory, often used synonymously with the term "short-term memory." However, many theorists clearly distinguish between the two concepts with regard to the manipulation of information in working memory. It temporarily retains information, including newly acquired information and memory content from long-term memory that is associated with the new information. In the model developed by Alan Baddeley and Graham Hitch, it includes a central executive, a phonological loop, an episodic buffer, and a visuospatial sketchpad.
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- Glossary
Archicortex
An ancient structure of the cerebrum in terms of evolutionary development, which, in contrast to the isocortex (also called the neocortex), has a three-layer structure. The archicortex mainly comprises the hippocampal structures.
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- Glossary
Area F5
A part of the ventral premotor cortex located in the frontal lobe of the mammalian brain. The nerve cells in this region of the brain are involved in planning and organizing purposeful movements, especially of the mouth and hand/grasping movements. Area F5 also has historical significance: it was here that researchers first discovered mirror neurons in macaques – the nerve cells in the brains of primates that fire just as strongly when their owners observe an action as when they perform it themselves.
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- Glossary
Praepiriform area
The praepiriform area is part of the piriform cortex in the ventral temporal lobe and belongs to the primary olfactory cortex, i.e., the primary olfactory cortex. Among other things, it contains inputs from the olfactory bulb (bulbus olfactorius) and is therefore involved in the initial cortical processing of olfactory stimuli.
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- Glossary
Asomatognosia
Asomatognosia literally means "not knowing" one's own body. The term refers to the loss of perception or feeling of belonging to one's own body parts. Asomatognosia is usually caused by damage to the right parietal lobe, which means that the left side of the body is usually affected.
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- Glossary
Association cortex
Parts of the cerebrum that are not assigned to the primary and secondary areas for sensory processing and motor function. They are mainly located in the neocortex, integrate information from multiple sources, are the center of thalamocortical and cortico-cortical networks, and cannot be clearly distinguished functionally.
